Occurrence and Biological Activity of Conjugated Linoleic Acid

Conjugated Linoleic Acid: Chemical Structure, Sources and Biological Properties

Conjugated linoleic acid (CLA) is a group of geometrical and positional isomers of linoleic acid (C18:2, cis-9, cis-12). In contrast to linoleic acid, double bonds in CLA are usually located at positions 9 and 11 or 10 and 12 and each double bond can be either in the cis or trans configuration. Meat and dairy products from ruminant animals (such as milk, butter, yogurt and cheese) are the princ...

Conjugated Linoleic Acid Targets

Conjugated Linoleic Acid

Conjugated linoleic acid, better known as CLA, is a fatty acid derived from the required nutrient, linoleic acid. The major structural difference between linoleic acid (an 18 carbon, polyunsaturated fatty acid) and CLA, is that linoleic acid has double bonds at carbons 9 and 12 in a cis configuration (methylene interrupted), while CLA has numerous isomers without methylene interrupted conjugate...

Atherosclerosis and conjugated linoleic acid.

Atherosclerosis can be defined as the development of abnormal fat deposits in the artery wall. Atherosclerotic lesions are believed to progress through a focal, lipid-filled foam cell stage (fatty streak) into an advanced, complicated lesion that contains abundant extracellular cholesterol ester in the atheromatous gruel within the arterial intima. Weakening of the arterial wall and/or rupture ...

Conjugated linoleic acid pork research.

The driving force behind most conjugated linoleic acid (CLA) research in swine has been related to potential improvements in animal production. Early work that used rodent models indicated that feeding CLA could potentially reduce body fat, increase lean content, increase growth rate, and improve feed conversion efficiency. Producer-backed funding organizations were, therefore, receptive to pro...